Catalogue A-Z
A / B / C / D / E / F / G / H / I / J / K / L / M / N / O / P / Q / R / S / T / U / V / W / X / Y / Z
ω-agatoxin IVA: is a specific blocker of P/Q-type calcium channel
Agelenin : suppresses the excitatory postsynaptic potentials possibly by blocking the presynaptic calcium channel
APETx2 : selectively blocks the H+-gated sodium channel ASIC3 (ACCN3). The blockade is rapid and reversible
Apamin : binds to the SK channels (small conductance Ca2+-activated K+ channels) in the brain and spinal cord and inhibits them
C
Charybdotoxin: Charybdotoxin blocks voltage gated and Ca2+ activated K+ channels
Chlorotoxin : binds to Cl- channels (small conductance epithelial chloride channels) in the brain and spinal cord and inhibits Cl- influx
Conantokin G : selectively inhibits NR2B subunits of N-methyl-D-aspartate (NMDA) receptor-mediated calcium influx in central nervous system neurons
Conopeptide Y pl1 : This toxin is an antagonist of voltage-gated K+ channels that belong to the Kv1 subfamily
Lys-Conopressin G: it is a vasopressin-like peptide
α - Conotoxin GI : acts on postsynaptic membranes, they bind to the nicotinic acetylcholine receptor (nAChR)
α - Conotoxin GID : acts on postsynaptic membranes
ω-Conotoxin GVIA: blocks specifically Cav2.2 channel
ω-Conotoxin MVIIA : acts at presynaptic membranes, they bind and block voltage-sensitive calcium channels (VSCC)
µ-Conotoxin PIIIA : bind and block site 1 of voltage-gated sodium channels
ω-Conotoxin SO-3 : selectively targets N-type voltage-sensitive calcium channels
ω-Conotoxin MVIIC : inhibits presynaptic calcium channels
α-Conotoxin IMI : acts on postsynaptic membranes, and binds onto and inhibits nicotinic acetylcholine receptors (nAChR)
α-Conotoxin MI : acts on postsynaptic membranes. It binds onto and blocks nicotinic acetylcholine receptors (nAChR)
GaTx2: is the most potent peptide inhibitor of ClC-2 chloride channel ever described.
GsMTx4: blocks mechanosensitive ion channels (strech-activated channel SAC)
Guangxitoxin 1E: inhibits Kv2.1 with an IC50 value of 1 nM and Kv2.2 with an IC50 value of 3 nM
Hemitoxin : blocks rat voltage-gated potassium channels Kv1.1 (KCNA1), Kv1.2 (KCNA2) and Kv1.3 (KCNA3) expressed in Xenopus oocytes
HsTx1 : it is one of the most potent toxins active on Kv1.3 channels (Kd close to 10pM)
Huwentoxin I : it is a selective inhibitor of N-type calcium channel, and TTXs channels
Huwentoxin IV : This lethal neurotoxin acts selectively on tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels, with an IC50 of 30nM in rat DRG neurons
Kaliotoxin 1 : Kaliotoxin-1 is a potent inhibitor of Kv channels
Leiurotoxin 1 (scyllatoxin): binds to the SK channels (small conductance Ca2+-activated K+ channels)
Margatoxin : is a potent selective inhibitor of voltage-dependent potassium channels such as Kv1.3
Maurocalcine : is a new member of the family of toxins acting on ryanodine receptors with an affinity in the 10nM range
Maurotoxin: inhibits Kv1.1, Kv1.2, Kv1.3 (preferentially Kv1.2), and apamin-sensitive SK channels
Morphiceptin: is one of the most potent selective agonist of µ-opoid receptor
Protoxin II (ProTx-II) : selective inhibitor of Nav1.7
Purotoxin 1: selective inhibitor of P2X3 receptor channel
Sarafotoxin A : presents a vasoconstrictor activity
Sarafotoxin B : presents a vasoconstrictor activity
Sarafotoxin C : presents a vasoconstrictor activity
ShK : inhibits voltage-dependent potassium channels
SNX482 : modulates the R-type current associated with the class α1E calcium channel (Cav2.3 from the CACNA1E gene)
Tamapin : binds to small conductance Ca2+-activated K+ channels (SK channels)
Tertiapin-Q : this is a neurotoxin with presynaptic activity that blocks the inwardly rectifying Kir1.1 (KCNJ1) and Kir3.1/3.4 (KCNJ3/KCNJ5) potassium channels with high affinity by binding to the M1-M2 linker region of these channels in a 1:1 stoichiometry
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