SAR Service

(Structure-activity relationship service)

Smartox Biotechnology can support your SAR projects including venom peptides or other types of cysteine-rich peptides, by synthesizing analogs in sufficient quality and quantity for your tests, over a short period of time and then identifying the pharmacophore by carrying out structural analysis. The pharmacophore identification of a complex peptide is a strategic step in the drug development process. It enables a decision to be made regarding whether a peptide of interest can be mimicked or not, which is invaluable information in the case of complex peptides. This kind of study requires a combination of expertise covering structural analysis and peptide synthesis.

Analog design

• Single amino-acids scan

• Truncation

• Mutations

• Etc.

Analogs synthesis

• Mg scale for in-vitro/vivo studies

• Purity > 95% or more

Structural studies

• NMR

• Circular dichroïsm

For more information please contact us at  This e-mail address is being protected from spambots. You need JavaScript enabled to view it