Sodium Channel

Protoxin II

Protoxin II is a selective inhibitor of Nav1.7

Huwentoxin IV

This lethal neurotoxin acts selectively on tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels, with an IC₅₀ of 30 nM in rat DRG neurons.
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Huwentoxin I

Huwentoxin I is a selective inhibitor of N-type calcium channels, and TTXs channels

μ-Conotoxin PIIIA

μ-Conotoxins binds and blocks site 1 of voltage-gated sodium channels.