Smartox’ ProTx-II, a highly potent Nav1.7 blocker

Interesting work on ProTx-II from the University College of London. ProTx-II is a potent blocker of the voltage-gated sodium channel Nav1.7. Results show that the synthetic Smartox’ ProTx-II is highly active.

View results here: http://discovery.ucl.ac.uk/1467249/1/Zoe%20Wright%20PhD%20Thesis.pdf

ProTx-II is also available with a fluorescent and a biotin tag.

 

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