Blockers and activators of tetrodotoxin R and S sodium channels
Modulators of tetrodotoxin S&R sodium channels
Smartox Biotechnology, specialized in animal peptide toxins synthesis, offers a wide range toxins that modulate ion channels. Among them, Smartox has developed a unique range of sodium channel blockers and activators including popular and innovative products. Nav channels are classified depending on their sensitivity to the widely used Tetrodotoxin (TTX) coming from puffer fish. Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6 and Nav1.7 sub-types are known to be TTX-sensitive and Nav1.5, Nav1.8 and Nav1.9 are TTX-resistant.
Smartox Nav toxins
|Tetrodotoxin sensitive channels|
|Tetrodotoxin resistant channels|
List of Smartox’s toxins and their preferential known Nav targets