ω-Tbo-IT1

Selective blocker of insects calcium channels

ω-Tbo-IT1 has been isolated from the venom of the Tibellus oblongus spider. ω-Tbo-IT1 is a selective blocker of insects calcium channels. It has been shown that ω-Tbo-IT1 has a potent insect toxicity with LD50 19 μg/g on house fly Musca domestica larvae and LD50 20 μg/g on juvenile Gromphadorhina portentosa cockroaches. Electrophysiological experiments revealed a reversible inhibition of evoked excitatory postsynaptic currents in blow fly Calliphora vicina neuromuscular junctions with an IC50 value 40 ± 10 nM.

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Product code: ITO001. Category: .

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Each month, Smartox Biotechnology is offering a toxin for absolutely free*! These toxins are being introduced in sample sizes so that you can experiment how well they work!

November 2017: ω-Tbo-IT

Discover ω-Tbo-IT1, a potent blocker of insect calcium channels

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ω-Tbo-IT1–New Inhibitor of Insect Calcium Channels Isolated from Spider Venom