Melittin

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Highly pure synthetic Melittin

Melittin is a major constituent of the bee venom of Apis mellifera. The N-terminal part of Melittin is hydrophobic and the C-terminal part is hydrophilic. Melittin accumulates in cell membrane which leads to various effects. It can be used to study lipid-protein interactions in membranes. Melittin has demonstrated interesting properties in pre-clinical studies as antimicrobial substance, as drug against rheumatoid arthritis, arteriosclerosis, cancer or as drug delivery system. Smartox Biotechnology offers highly pure synthetic Melittin.

SKU: MEL01 Category:

Description

AA sequence: GIGAVLKVLTTGLPALISWIKRKRQQ-NH2
Length (aa): 26
Formula: C131H229N39O31
Molecular Weight: 2846,56 Da
Appearance: white lyophilized solid
Solubility: water or saline buffer
CAS number: 20449-79-0
Source: synthetic
Purity rate: > 95 %

  • Apamin: SK channel blocker from bee venom

Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and biotechnological Use: Melittin, Apamin and Mastoparan.

Conformational States of Melittin at a Bilayer Interface.

Melittin: a membrane-active peptide with diverse functions

The actions of melittin on membranes

 

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    Melittin

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